Abstract objectives: recent studies have indicated that excessive fat may confound assessment of diffusion in organs with high fat content, such as the liver and breast however, the extent of this effect in the kidney, which is not considered a major fat deposition site, remains unc. Assessment with apparent diffusion coefﬁcient1 fusion effects is mandatory to obtain an echo-planar imaging sequence with fat saturation (2,500/102 13. Citation: blackledge md, collins dj, tunariu n, orton mr, padhani ar, et al (2014) assessment of treatment response by total tumor volume and global apparent diffusion coefficient using diffusion-weighted mri in patients with metastatic bone disease: a feasibility study. The effect of region of interest strategies on apparent diffusion coefficient assessment in patients treated with palliative radiation therapy to brain metastases.
Objectives: recent studies have indicated that excessive fat may confound assessment of diffusion in organs with high fat content, such as the liver and breast. Objective: the aim of this study was to evaluate the changes in t 2 values and apparent diffusion coefficient (adc) in the masseter muscle by clenching in healthy volunteers. Given the potential confounding effect of fat on apparent diffusion coefficient (adc) in the liver, we have assessed diffusion tensor imaging in liver fibrosis with minimal effect of fat on adc and fractional anisotropy (fa.
Apparent diffusion coefficient (adc) estimates in a temperature-controlled phantom and abdominal and pelvic organs in healthy volunteers methods: geometric distortion, ghosting, fat suppression, and repeatability and homogeneity of. Methods: using computer simulations, we investigated the effect of fat on assessment of apparent diffusion coefficient (adc), intravoxel incoherent motion (ivim), and tcm-derived pure-diffusivity we also investigated the influence of magnetic resonance repetition (tr) and echo time (te) on dwi parameters as a result of variation in the. Objective the purpose of this article is to evaluate the relationship between apparent diffusion coefficient (adc) values, tumor volume, and total gleason grade in patients with prostate cancer before radical prostatectomymaterials and methods. To investigate the effect of fat infiltration on the apparent diffusion coefficient (adc) of liver, and assess the relationship between adc and hepatic fat fraction (hff.
Dw-mri has been attempted in the lung for staging and the quantitative parameter, the apparent diffusion coefficient (adc), has been explored for differentiating benign from. To establish repeatability of apparent diffusion coefficients (adcs) acquired from free-breathing diffusion-weighted magnetic resonance imaging (dw-mri) in malignant lung lesions and investigate effects of lesion size, location and respiratory motion free-breathing dw-mri of whole lung achieves. The role of diffusion-weighted (dw) magnetic resonance (mr) imaging with quantitative apparent diffusion coefficients (adcs) in the pretreatment evaluation of glioma grade has been investigated in various studies (2,6-11. Apparent diffusion coefficient (adc) is a measure of the magnitude of diffusion (of water molecules) within tissue, and is commonly clinically calculated using mri with diffusion weighted imaging (dwi) 1.
Keywords: breast cancer, diffusion-weighted mri (dwi), apparent diffusion coefficient (adc), fat suppression, breast density introduction magnetic resonance imaging (mri) is proving to be valuable for the detection and treatment monitoring of breast cancer. Original article effects of contrast-enhancement on diffusion weighted imaging and apparent diffusion coefficient measurements in 3-t magnetic resonance imaging. There is a large volume of published research into the use of diffusion-weighted imaging and apparent diffusion coefficients (adc) in prediction and response assessment in patients undergoing neoadjuvant chemotherapy (nac) for breast cancer but despite this, dwi is not routinely used for response assessment in clinical practice. Objective the objectives of this study were to define the range of apparent diffusion coefficients (adcs) from whole-body dwi in normal abdominal organs and bone marrow, to identify adc differences between sexes and changes occurring with age, and to evaluate the effect of the fat fraction (ff) on the adc of normal liver parenchyma and bone marrow.
The method enables whole-body estimates of global apparent diffusion coefficient (gadc) and total diffusion volume (tdv), both of which have demonstrated considerable utility for assessing. Apparent diffusion coefficient (adc) maps were generated using a monoexponential fit on each of four slices, two to three linear regions-of-interest were placed on each joint normalized adc (nadc) values were defined as joint adc divided by a reference adc derived from normal sacral bone. To establish standard apparent diffusion coefficient (adc) and the fat content as a function of age, gender and body mass index (bmi) in healthy parotid glands, and to address the influences of fat suppression on adc measurements a total of 100 healthy adults (gender and age evenly distributed.
Maeda, m, kato, h, sakuma, h usefulness of the apparent diffusion coefficient in line scan diffusion-weighted imaging for distinguishing between squamous cell carcinomas and malignant lymphomas of the head and neck. For example, early changes in apparent diffusion coefficient (adc) values after chemoembolization have been shown to predict long term outcomes [4,5] dw-mri is an appealing imaging tool as it can be readily performed on conventional mri systems and can report on fundamental tumor biology.